A recent study in China involving 300 women established that oral misoprostol was just as effective as intravenous Oxytocin. The study also found that there was no difference in adverse effects and birth complications. Because fixed-dose misoprostol can lead to higher frequency of excessive uterine contractility that results in fetal distress, the study used titrated, small doses of oral misoprostol.
Source reference:
Titrated Oral Compared With Vaginal Misoprostol for Labor Induction: A Randomized Controlled Trial
Oral Misoprostol (Cytotec) Possibly as Effective in Inducing Labor as Intravenous Oxytocin (8.24.10)
August 24, 2010
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